PozNews - HIV News - STD News: The Role of Infection in Carotid Plaque Pathogenesis and Stability: The Clinical Evidence. The Role of Infection in Carotid Plaque Pathogenesis and Stability: The Clinical Evidence. ================================================================================ MedWorm on 24 February, 2010 01:00:00 CONCLUSION: There is considerable evidence supporting the contribution of other commonly encountered pathogens in the pathogenesis and rupture of the carotid plaque. Research in this direction should not be abandoned and further studies are necessary to elucidate the exact role of common infections in the pathogenesis and development of CPD and how this can be translated into novel pharmacological approaches for prevention and treatment. PMID: 20180770 [PubMed - as supplied by publisher] (Source: Current Vascular Pharmacology)