Seminal plasma HIV levels in men with asymptomatic sexually transmitted infections

The effect of asymptomatic sexually transmitted urethral infections on human immunodeficiency virus (HIV) RNA viral load in semen is poorly defined. We studied five such patients. Those on antiretrovirals (n = 2) had lower seminal plasma viral loads (SPVL) (2.11 and 1.98 log10 copies/mL) than those not on antiretrovirals (n = 3) (2.27–3.78 log10 copies/mL). One patient who was not taking antiretrovirals had a 94% decline in SPVL after treatment of asymptomatic Chlamydia trachomatis urethritis, suggesting that asymptomatic infection may be a co-factor for HIV transmission. (Source: International Journal of STD and AIDS)

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